Postoperative Packing of Perianal Abscess Cavities (PPAC2): randomized clinical trial.

ABSTRACT:

Background

Perianal abscess is common. Traditionally, postoperative perianal abscess cavities are managed with internal wound packing, a practice not supported by evidence. The aim of this randomized clinical trial (RCT) was to assess if non-packing is less painful and if it is associated with adverse outcomes.

Methods

The Postoperative Packing of Perianal Abscess Cavities (PPAC2) trial was a multicentre, RCT (two-group parallel design) of adult participants admitted to an NHS hospital for incision and drainage of a primary perianal abscess. Participants were randomized 1:1 (via an online system) to receive continued postoperative wound packing or non-packing. Blinded data were collected via symptom diaries, telephone, and clinics over 6 months. The objective was to determin

SUBMITTER: Newton K 

PROVIDER: S-EPMC10364677 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature