Major surgical postoperative complications and survival in breast cancer: Swedish population-based register study in 57 152 women.

ABSTRACT:

Background

Postoperative complications may activate prometastatic systemic pathways through tissue damage, wound healing, infection, and inflammation. Postoperative complications are associated with inferior survival in several types of cancer. The aim was to determine the association between postoperative complications and survival in breast cancer.

Methods

This population-based cohort included women operated for T1-3 N0-3 M0 invasive breast cancer in Sweden from 2008 to 2017. Only major surgical postoperative complications leading to readmission and/or reoperation within 30 days were considered. Main outcomes were overall survival (OS) and breast cancer-specific survival (BCSS). Prospectively collected nationwide register data were used. Multivariable Cox models were adjus

SUBMITTER: de Boniface J 

PROVIDER: S-EPMC10364684 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature