Risks for donors associated with living kidney donation: meta-analysis.

ABSTRACT:

Background

Living kidney donation risk is likely to differ according to donor's demographics. We aimed to analyse the effects of age, sex, body mass index (BMI) and ethnicity.

Methods

A systematic review and meta-analysis was undertaken of the effects of preoperative patient characteristics on donor kidney function outcomes, surgical complications, and hypertension.

Results

5129 studies were identified, of which 31 met the inclusion criteria, mainly from the USA and Europe. The estimated glomerular filtration rate (eGFR) in donors aged over 60 years was a mean of 9.54 ml per min per 1.73 m2 lower than that of younger donors (P < 0.001). Female donors had higher relative short- and long-term survival. BMI of over 30 kg/m2 was found to significantly lower the donor's eG

SUBMITTER: Bellini MI 

PROVIDER: S-EPMC10364766 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature