Centralized repeated resectability assessment of patients with colorectal liver metastases during first-line treatment: prospective study.

ABSTRACT:

Background

Metastasectomy is probably underused in metastatic colorectal cancer. The aim of this study was to investigate the effect of centralized repeated assessment on resectability rate of liver metastases.

Methods

The prospective RAXO study was a nationwide study in Finland. Patients with treatable metastatic colorectal cancer at any site were eligible. This planned substudy included patients with baseline liver metastases between 2012 and 2018. Resectability was reassessed by the multidisciplinary team at Helsinki tertiary referral centre upfront and twice during first-line systemic therapy. Outcomes were resectability rates, management changes, and survival.

Results

Of 812 patients included, 301 (37.1 per cent) had liver-only metastases. Of these, tumours were

SUBMITTER: Isoniemi H 

PROVIDER: S-EPMC10364914 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature