Red blood cell distribution width to platelet ratio in neonatal foals with sepsis.

ABSTRACT:

Background

Rapid and accurate markers to aid diagnosis of sepsis are needed in neonatal foals. The CBC variable red blood cell distribution width (RDW) to platelet ratio (RPR) is associated with inflammatory response and linked to poor outcomes of sepsis in human patients.

Hypothesis

Explore the correlation of RPR with sepsis in neonatal foals and evaluate RPR predictive and prognostic value.

Animals

Three hundred seventeen hospitalized neonatal foals ≤7 days of age that had a CBC and physical exam performed at admission between 2012 and 2021.

Methods

Retrospective case-control study. Clinical records were used to calculate sepsis scores and define groups. Red blood cell distribution width to platelet ratio was calculated and compared between groups (septic vs

SUBMITTER: Scalco R 

PROVIDER: S-EPMC10365058 | biostudies-literature | 2023 Jul-Aug

REPOSITORIES: biostudies-literature