Preliminary construct validity of patient-reported outcomes to assess chronic pain in adults with sickle cell disease.

ABSTRACT: Chronic pain affects 30% to 40% of individuals with sickle cell disease (SCD) and impairs patient functioning. Clinically meaningful, practical, and valid assessment tools for investigation, evaluation, and management of chronic pain are limited, representing a barrier for advancing SCD care. We sought to determine whether patient-reported outcomes (PROs) show preliminary construct validity in identifying individuals with SCD who were a priori defined as suggestive of having chronic pain based on previously published criteria. All individuals completed the Patient-Reported Outcomes Measurement Information System (PROMIS) domains: pain interference, pain behavior, pain quality (nociceptive, neuropathic), fatigue, sleep disturbance, depression, and anxiety; the Adult Sickle Cell Quality of L

SUBMITTER: Mucalo L 

PROVIDER: S-EPMC10365933 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature