Assessment of gut microbial β-glucuronidase and β-glucosidase activity in women with polycystic ovary syndrome.

ABSTRACT: PCOS is a prevalent endocrine disorder among women of reproductive age, characterized by hormonal imbalances and metabolic disturbances. This study explores the correlation between gut microbial β-glucuronidase and β-glucosidase and PCOS, focusing on their association with hormone levels and other clinical parameters. In this case-control study, fecal samples were collected from women of reproductive age, both with and without PCOS. The analysis of gut β-glucuronidase and β-glucosidase enzymes was conducted with the other clinical parameters, including body mass index, hormone levels, and hirsutism. These factors were then subjected to correlation analysis. PCOS women showed significantly higher levels of β-glucuronidase activity with a statistically significant P-value (0.05 ± 0.1 vs. 0.0

SUBMITTER: Patel J 

PROVIDER: S-EPMC10366212 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature