Modeling vaccination coverage during the 2022 central Ohio measles outbreak: a cross-sectional study.

ABSTRACT:

Background

Of the eight large (>50 cases) US postelimination outbreaks, the first and last occurred in Ohio. Ohio's vaccination registry is incomplete. Community-level immunity gaps threaten more than two decades of measles elimination in the US. We developed a statistical model, VaxEstim, to rapidly estimate the early-phase vaccination coverage and immunity gap in the exposed population during the 2022 Central Ohio outbreak.

Methods

We used reconstructed daily incidence (from publicly available data) and assumptions about the distribution of the serial interval, or the time between symptom onset in successive measles cases, to estimate the effective reproduction number (i.e., the average number of secondary infections caused by an infected individual in a partially immune p

SUBMITTER: Martoma RA 

PROVIDER: S-EPMC10366459 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature