Role of macrophage scavenger receptor 1 in the progression of dyslipidemia in acne vulgaris patients.

ABSTRACT:

Background

Macrophage scavenger receptor 1 gene (MSR1), is responsible for producing macrophage scavenger receptors. MSR1 is primarily located on the surfaces of various macrophage types and is known to exert a range of effects on the human body. These effects include influencing innate and adaptive immunological reactions, as well as contributing to the development of conditions such as atherosclerosis, dyslipidemia, liver and lung disease, and cancer. The unregulated assimilation of lipoproteins by MSR1 leads to the creation of macrophages rich in cholesterol that manifest as foam-like cells, ultimately contributing to dyslipidemia. This occurrence highlights the significance of MSR1 as a key player in the pathophysiology of dyslipidemia.

Aim

In this study, we aimed to est

SUBMITTER: AbdElneam AI 

PROVIDER: S-EPMC10366491 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature