Dataset Information

A Sticky Situation: An Uncommon Cardiac Complication of Cyanoacrylate Glue Injection.

ABSTRACT: This case report describes an uncommon cardiac complication related to the endoscopic injection of cyanoacrylate glue to treat gastric variceal bleeding. The presentation and management options are reviewed and compared with our step-by-step approach in a patient requiring a liver transplant. (Level of Difficulty: Advanced.).

SUBMITTER: Sindhi RMS

PROVIDER: S-EPMC10366504 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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Publications

A Sticky Situation: An Uncommon Cardiac Complication of Cyanoacrylate Glue Injection.

Sindhi Rithik Mohan Singh RMS Win Kyaw Z KZ Zafar Athesham A Steeds Richard P RP

JACC. Case reports 20230705

This case report describes an uncommon cardiac complication related to the endoscopic injection of cyanoacrylate glue to treat gastric variceal bleeding. The presentation and management options are reviewed and compared with our step-by-step approach in a patient requiring a liver transplant. (<b>Level of Difficulty: Advanced.</b>). ...[more]

PMID: 37496721

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Project description:Malaria eradication involves eliminating malaria from every country where transmission occurs. Current theory suggests that the post-elimination challenges of remaining malaria-free by stopping transmission from imported malaria will have onerous operational and financial requirements. Although resurgent malaria has occurred in a majority of countries that tried but failed to eliminate malaria, a review of resurgence in countries that successfully eliminated finds only four such failures out of 50 successful programmes. Data documenting malaria importation and onwards transmission in these countries suggests malaria transmission potential has declined by more than 50-fold (i.e. more than 98%) since before elimination. These outcomes suggest that elimination is a surprisingly stable state. Elimination's 'stickiness' must be explained either by eliminating countries starting off qualitatively different from non-eliminating countries or becoming different once elimination was achieved. Countries that successfully eliminated were wealthier and had lower baseline endemicity than those that were unsuccessful, but our analysis shows that those same variables were at best incomplete predictors of the patterns of resurgence. Stability is reinforced by the loss of immunity to disease and by the health system's increasing capacity to control malaria transmission after elimination through routine treatment of cases with antimalarial drugs supplemented by malaria outbreak control. Human travel patterns reinforce these patterns; as malaria recedes, fewer people carry malaria from remote endemic areas to remote areas where transmission potential remains high. Establishment of an international resource with backup capacity to control large outbreaks can make elimination stickier, increase the incentives for countries to eliminate, and ensure steady progress towards global eradication. Although available evidence supports malaria elimination's stickiness at moderate-to-low transmission in areas with well-developed health systems, it is not yet clear if such patterns will hold in all areas. The sticky endpoint changes the projected costs of maintaining elimination and makes it substantially more attractive for countries acting alone, and it makes spatially progressive elimination a sensible strategy for a malaria eradication endgame.

Dataset Information

A Sticky Situation: An Uncommon Cardiac Complication of Cyanoacrylate Glue Injection.

Publications

A Sticky Situation: An Uncommon Cardiac Complication of Cyanoacrylate Glue Injection.

Similar Datasets

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