Classification of microvascular invasion of hepatocellular carcinoma: correlation with prognosis and magnetic resonance imaging.

ABSTRACT:

Background/aims

The microvascular invasion (MVI) of hepatocellular carcinoma (HCC) involves a wide histological spectrum, and it is unclear whether the degree of MVI correlates with patient prognosis or imaging findings. Here, we evaluate the prognostic value of MVI classification and analyze the radiologic features predictive of MVI.

Methods

Using a retrospective cohort of 506 patients with resected solitary HCCs, the histological and imaging features of MVI were reviewed and correlated with clinical data.

Results

MVI-positive HCCs invading ≥5 vessels or those with ≥50 invaded tumor cells were significantly associated with decreased overall survival (OS). The 5-year OS, recurrence-free survival (RFS), and beyond Milan criteria RFS rates were significantly poorer in p

SUBMITTER: Hwang YJ 

PROVIDER: S-EPMC10366800 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature