Comparison of Total Body Vitamin A Stores Using Individual versus Population ¹³C-Natural Abundance of Serum Retinol in Preschool Children and Women Residing in 6 Diverse African Countries.

ABSTRACT:

Background

Stable isotope techniques using ¹³C to assess vitamin A (VA) dietary sources, absorption, and total body VA stores (TBSs) require determination of baseline ¹³C abundance. ¹³C-natural abundance is approximately 1.1% total carbon, but varies with foods consumed, supplements taken, and food fortification with synthetic retinyl palmitate.

Objectives

We determined ¹³C variation from purified serum retinol and the resulting impact on TBSs using pooled data from preschool children in Burkina Faso, Cameroon, Ethiopia, South Africa, Tanzania, and Zambia and Zambian women.

Methods

Seven studies included children (n = 639; 56 ± 25 mo; 48% female) and one in women (n = 138; 29 ± 8.5 y). Serum retinol ¹³C-natural ab

SUBMITTER: Gannon BM 

PROVIDER: S-EPMC10367224 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature