A systematic review and meta-analysis of the effect of high-intensity statin on coronary microvascular dysfunction.

ABSTRACT:

Objective

The purpose of this meta-analysis is to evaluate the role of high-intensity statin pretreatment on coronary microvascular dysfunction in patients with coronary heart disease undergoing percutaneous coronary intervention (PCI).

Methods

PubMed, Cochrane, and Embase were searched. This meta-analysis selection included randomized controlled trials (RCTs), involving high-intensity statin pretreatment as active treatment, and measurement of thrombolysis in myocardial infarction (TIMI), myocardial blush grade (MBG) or index of microvascular resistance (IMR) in coronary heart disease (CHD) patients undergoing PCI. I² test was used to evaluate heterogeneity. Pooled effects of continuous variables were reported as Standard mean difference (SMD) and 95% confidence

SUBMITTER: Huang B 

PROVIDER: S-EPMC10367265 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature