Green and white MEKC for determination of different anti-diabetic binary mixtures and their triple-combo pill.

ABSTRACT: The work introduces green and white sustainable micellar electrokinetic chromatography (MEKC) procedure that could analyze therapeutically related drugs, empagliflozin (EMP), linagliptin (LIN) and metformin (MET) which are antidiabetic drugs with different mechanism of action, in their different pharmaceutical combinations. The method not only comply with the green analytical concepts, but also it is in line with sustainable analytical concepts as it is economic by applying the same operating conditions to analyze different pharmaceuticals in quality control (QC) labs which is a crucial step in QC labs and research centers to save time, effort, and money. Moreover, the method functionality regarding its scope with its achieved levels of accuracy, precision, low detection, and quantitation

SUBMITTER: Ahmed AR 

PROVIDER: S-EPMC10367405 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature