Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma.

ABSTRACT:

Background

Black and Latinx patients bear a disproportionate burden of asthma. Efforts to reduce the disproportionate morbidity have been mostly unsuccessful, and guideline recommendations have not been based on studies in these populations.

Methods

In this pragmatic, open-label trial, we randomly assigned Black and Latinx adults with moderate-to-severe asthma to use a patient-activated, reliever-triggered inhaled glucocorticoid strategy (beclomethasone dipropionate, 80 μg) plus usual care (intervention) or to continue usual care. Participants had one instructional visit followed by 15 monthly questionnaires. The primary end point was the annualized rate of severe asthma exacerbations. Secondary end points included monthly asthma control as measured with the Asthma Control T

SUBMITTER: Israel E 

PROVIDER: S-EPMC10367430 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature