Use of permethrin and other pyrethroids and mortality in the Agricultural Health Study.

ABSTRACT:

Objectives

Pyrethroid insecticides have been linked with multiple health outcomes. One study reported an association with increased all-cause and cardiovascular mortality. Given the widespread use of pyrethroids, these findings warrant confirmation. We explored associations of permethrin/pyrethroid use with overall and cause-specific mortality among 50 665 licensed pesticide applicators in the Agricultural Health Study.

Methods

At enrolment (1993-1997), participants self-reported information on permethrin/pyrethroid use. Information on causes of death came from linkage with death registries through 2016. We used Cox proportional hazards models to estimate HRs and 95% CIs with adjustment for potential confounders.

Results

Over an average 21 years of follow-up, 19.6% (9

SUBMITTER: Shrestha S 

PROVIDER: S-EPMC10368161 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature