Ontology highlight
ABSTRACT:
SUBMITTER: Zhou L
PROVIDER: S-EPMC10368701 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Communications biology 20230725 1
Nuclear factor I B (NFIB) plays an important role in tumors. Our previous study found that NFIB can promote colorectal cancer (CRC) cell proliferation in acidic environments. However, its biological functions and the underlying mechanism in CRC are incompletely understood. Nicotinamide adenine dinucleotide (NAD+) effectively affects cancer cell proliferation. Nevertheless, the regulatory mechanism of NAD+ synthesis in cancer remains to be elucidated. Here we show NFIB promotes CRC proliferation ...[more]