Dataset Information

A comprehensive multi-domain dataset for mitotic figure detection.

ABSTRACT: The prognostic value of mitotic figures in tumor tissue is well-established for many tumor types and automating this task is of high research interest. However, especially deep learning-based methods face performance deterioration in the presence of domain shifts, which may arise from different tumor types, slide preparation and digitization devices. We introduce the MIDOG++ dataset, an extension of the MIDOG 2021 and 2022 challenge datasets. We provide region of interest images from 503 histological specimens of seven different tumor types with variable morphology with in total labels for 11,937 mitotic figures: breast carcinoma, lung carcinoma, lymphosarcoma, neuroendocrine tumor, cutaneous mast cell tumor, cutaneous melanoma, and (sub)cutaneous soft tissue sarcoma. The specimens were processed in several laboratories utilizing diverse scanners. We evaluated the extent of the domain shift by using state-of-the-art approaches, observing notable differences in single-domain training. In a leave-one-domain-out setting, generalizability improved considerably. This mitotic figure dataset is the first that incorporates a wide domain shift based on different tumor types, laboratories, whole slide image scanners, and species.

SUBMITTER: Aubreville M

PROVIDER: S-EPMC10368709 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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A comprehensive multi-domain dataset for mitotic figure detection.

Aubreville Marc M Wilm Frauke F Stathonikos Nikolas N Breininger Katharina K Donovan Taryn A TA Jabari Samir S Veta Mitko M Ganz Jonathan J Ammeling Jonas J van Diest Paul J PJ Klopfleisch Robert R Bertram Christof A CA

Scientific data 20230725 1

The prognostic value of mitotic figures in tumor tissue is well-established for many tumor types and automating this task is of high research interest. However, especially deep learning-based methods face performance deterioration in the presence of domain shifts, which may arise from different tumor types, slide preparation and digitization devices. We introduce the MIDOG++ dataset, an extension of the MIDOG 2021 and 2022 challenge datasets. We provide region of interest images from 503 histolo ...[more]

PMID: 37491536

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Project description:The use of small and remotely controlled unmanned aerial vehicles (UAVs), referred to as drones, has increased dramatically in recent years, both for professional and recreative purposes. This goes in parallel with (intentional or unintentional) misuse episodes, with an evident threat to the safety of people or facilities [1]. As a result, the detection of UAV has also emerged as a research topic [2]. Most of the existing studies on drone detection fail to specify the type of acquisition device, the drone type, the detection range, or the employed dataset. The lack of proper UAV detection studies employing thermal infrared cameras is also acknowledged as an issue, despite its success in detecting other types of targets [2]. Beside, we have not found any previous study that addresses the detection task as a function of distance to the target. Sensor fusion is indicated as an open research issue as well to achieve better detection results in comparison to a single sensor, although research in this direction is scarce too [3], [4], [5], [6]. To help in counteracting the mentioned issues and allow fundamental studies with a common public benchmark, we contribute with an annotated multi-sensor database for drone detection that includes infrared and visible videos and audio files. The database includes three different drones, a small-sized model (Hubsan H107D+), a medium-sized drone (DJI Flame Wheel in quadcopter configuration), and a performance-grade model (DJI Phantom 4 Pro). It also includes other flying objects that can be mistakenly detected as drones, such as birds, airplanes or helicopters. In addition to using several different sensors, the number of classes is higher than in previous studies [4]. The video part contains 650 infrared and visible videos (365 IR and 285 visible) of drones, birds, airplanes and helicopters. Each clip is of ten seconds, resulting in a total of 203,328 annotated frames. The database is complemented with 90 audio files of the classes drones, helicopters and background noise. To allow studies as a function of the sensor-to-target distance, the dataset is divided into three categories (Close, Medium, Distant) according to the industry-standard Detect, Recognize and Identify (DRI) requirements [7], built on the Johnson criteria [8]. Given that the drones must be flown within visual range due to regulations, the largest sensor-to-target distance for a drone in the dataset is 200 m, and acquisitions are made in daylight. The data has been obtained at three airports in Sweden: Halmstad Airport (IATA code: HAD/ICAO code: ESMT), Gothenburg City Airport (GSE/ESGP) and Malmö Airport (MMX/ESMS). The acquisition sensors are mounted on a pan-tilt platform that steers the cameras to the objects of interest. All sensors and the platform are controlled with a standard laptop vis a USB hub.

Dataset Information

A comprehensive multi-domain dataset for mitotic figure detection.

Publications

A comprehensive multi-domain dataset for mitotic figure detection.

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