Frailty and Clinical Outcomes in Patients Treated With Hemodialysis: A Prospective Cohort Study.

ABSTRACT:

Rationale and objective

Frailty is common among people with kidney failure treated with hemodialysis (HD). The objective was to describe how frailty evolves over time in people treated by HD, how improvements in frailty and frailty markers are associate with clinical outcomes, and the characteristics that are associated with improvement in frailty.

Study design

Prospective cohort study.

Setting and participants

Adults initiating thrice weekly in-center HD in Canada.

Exposure

We classified frailty using a 5-point score (3 or more indicates frailty) based on physical inactivity, slowness or weakness, poor endurance or exhaustion, and malnutrition. We categorized the frailty trajectory as never present, improving, deteriorating, and always present.

Outcomes

SUBMITTER: Tonelli M 

PROVIDER: S-EPMC10368915 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature