Cortico-Cerebellar neurodynamics during social interaction in Autism Spectrum Disorders.

ABSTRACT:

Background

Exploring neural network dynamics during social interaction could help to identify biomarkers of Autism Spectrum Disorders (ASD). A cerebellar involvement in autism has long been suspected and recent methodological advances now enable studying cerebellar functioning in a naturalistic setting. Here, we investigated the electrophysiological activity of the cerebro-cerebellar network during real-time social interaction in ASD. We focused our analysis on theta oscillations (3-8 Hz), which have been associated with large-scale coordination of distant brain areas and might contribute to interoception, motor control, and social event anticipation, all skills known to be altered in ASD.

Methods

We combined the Human Dynamic Clamp, a paradigm for studying realistic social

SUBMITTER: Gaudfernau F 

PROVIDER: S-EPMC10368923 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature