Could circulating biomarkers of nitrosative stress and protein glycoxidation be useful in patients with gastric cancer?

ABSTRACT:

Background

Nitrosative stress leads to protein glycoxidation, but both processes may be strongly related to the cancer development. Therefore, the aim of this study was to assess the nitrosative stress and protein glycoxidation products in patients with gastric cancer in comparison with healthy controls. We are also the first to evaluate the diagnostic utility of nitrosative stress and protein glycoxidation markers in gastric cancer patients in respect to histopathological classifications (TNM, Lauren's and Goseki's classification) and histopathological parameters such as histological type, histological differentiation grade, presence of vascular or neural invasion, desmoplasia and Helicobacter pylori infection.

Methods

The study included 50 patients with gastric canc

SUBMITTER: Dorf J 

PROVIDER: S-EPMC10369187 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature