Disentangling global and domain-level adaptive behavior trajectories among children with autism spectrum disorder.

ABSTRACT:

Background

Heterogeneity in adaptive behavior abilities among people with autism spectrum disorder (ASD) is expressed not only as uneven levels of impairment across domains, but also in the developmental trajectories of adaptive skills. We studied the question of whether, after accounting for global adaptive behavior development, we find evidence of heterogeneity in the trajectories of specific domains of adaptive behavior.

Methods

A sample of 504 children with ASD was obtained by combining data from two independent natural history studies conducted in North America. We used a factor of curves model to explain growth between 36 and 138 months in Vineland Adaptive Behavior Scales, Second Edition (VABS) age equivalents as a function of domain-specific and global growth process

SUBMITTER: Farmer C 

PROVIDER: S-EPMC10369325 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature