Economic burden of antimicrobial resistance and inappropriate empiric treatment in Thailand.

ABSTRACT:

Objective

To quantify the economic burden of bacterial antimicrobial resistance in Thailand and estimate potential savings from improving the rate of appropriate empiric treatment, where effective coverage is provided within the first days of infection.

Design

Cost-of-illness study.

Methods

A cost-calculator, decision-tree model was developed using published data and records from 3 Thai hospitals for patients hospitalized with antimicrobial-resistant infections between 2015 and 2019. Direct and indirect costs of antimicrobial-resistant infections were assessed over a 5-year time horizon, with outcomes derived separately for cases having received appropriate empiric treatment versus inappropriate empiric treatment. In a real-world scenario, outcomes were estimated usin

SUBMITTER: Kongnakorn T 

PROVIDER: S-EPMC10369446 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature