Neurodevelopmental impairments in children with septo-optic dysplasia spectrum conditions: a systematic review.

ABSTRACT:

Background

Septo-optic dysplasia (SOD) is a rare condition diagnosed in children with two or more of the following: hypopituitarism, midline brain abnormalities, and optic nerve hypoplasia. Children with SOD experience varied visual impairment and endocrine dysfunction. Autistic-like behaviours have been reported; however, their nature and prevalence remain to be fully understood. The present systematic review aimed to explore the type and prevalence of neurodevelopmental impairments in children with SOD spectrum conditions.

Methods

The search was conducted in PubMed, EMBASE, and PsycInfo. Hand-searching reference lists of included studies was conducted. All peer-reviewed, observational studies assessing behavioural and cognitive impairments or autism spectrum disorder (ASD)

SUBMITTER: Mann A 

PROVIDER: S-EPMC10369759 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature