Nucleus accumbens core single cell ensembles bidirectionally respond to experienced versus observed aversive events.

ABSTRACT: Empathy is the ability to adopt others' sensory and emotional states and is an evolutionarily conserved trait among mammals. In rodents, empathy manifests itself as social modulation of aversive stimuli such as acknowledging and acting on conspecifics' distress. The neuronal network underlying social transmission of information is known to overlap with the brain regions that mediate behavioral responses to aversive and rewarding stimuli. In this study, we recorded single cell activity patterns of nucleus accumbens (NAc) core neurons using in vivo optical imaging of calcium transients via miniature scopes. This cutting-edge imaging methodology not only allows us to record activity patterns of individual neurons but also lets us longitudinally follow these individual neurons across time and

SUBMITTER: Dinckol O 

PROVIDER: S-EPMC10370069 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature