Speak and you shall predict: speech at initial cocaine abstinence as a biomarker of long-term drug use behavior.

ABSTRACT:

Importance

Valid biomarkers that can predict longitudinal clinical outcomes at low cost are a holy grail in psychiatric research, promising to ultimately be used to optimize and tailor intervention and prevention efforts.

Objective

To determine if baseline linguistic markers in natural speech, as compared to non-speech clinical and demographic measures, can predict drug use severity measures at future sessions in initially abstinent individuals with cocaine use disorder (iCUD).

Design

A longitudinal cohort study (August 2017 - March 2020), where baseline measures were used to predict outcomes collected at three-month intervals for up to one year of follow-up.

Participants

Eighty-eight initially abstinent iCUD were studied at baseline; 57 (46 male, age 50.7+/-7.

SUBMITTER: Agurto C 

PROVIDER: S-EPMC10370100 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature