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Considerations for Generating Frequency Modulation Waveforms for Fourier Transform-Ion Mobility Experiments.


ABSTRACT: By casting the information regarding an ion population's mobility in the frequency domain, the coupling of time-dispersive ion mobility techniques is now imminently compatible with slower mass analyzers such as ion traps. Recent reports have detailed the continued progress toward maximizing the efficiency of the Fourier transform ion mobility-mass spectrometry (FT-IM-MS) experiments, but few reports have outlined the intersection between the practical considerations of implementation against the theoretical limits imposed by traditional signal processing techniques. One of the important concerns for Fourier-based multiplexing experiments is avoiding signal aliasing as a product of undersampled signals that may occur during data acquisition. In addition to traditional considerations such as

SUBMITTER: Cabrera ER 

PROVIDER: S-EPMC10370403 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature