A retrospective evaluation of Bayesian-penalized likelihood reconstruction for [¹⁵O]H₂O myocardial perfusion imaging.

ABSTRACT:

Background

New Block-Sequential-Regularized-Expectation-Maximization (BSREM) image reconstruction technique has been introduced for clinical use mainly for oncologic use. Accurate and quantitative image reconstruction is essential in myocardial perfusion imaging with positron emission tomography (PET) as it utilizes absolute quantitation of myocardial blood flow (MBF). The aim of the study was to evaluate BSREM reconstruction for quantitation in patients with suspected coronary artery disease (CAD).

Methods and results

We analyzed cardiac [¹⁵O]H₂O PET studies of 177 patients evaluated for CAD. Differences between BSREM and Ordered-Subset-Expectation-Maximization with Time-Of-Flight (TOF) and Point-Spread-Function (PSF) modeling (OSEM-TOF-PSF) in terms o

SUBMITTER: Siekkinen R 

PROVIDER: S-EPMC10371909 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature