Should embryo rebiopsy be considered a regular strategy to increase the number of embryos available for transfer?

ABSTRACT:

Purpose

To investigate whether embryo rebiopsy increases the yield of in vitro fertilization (IVF) cycles.

Methods

Retrospective study including 18,028 blastocysts submitted for trophectoderm biopsy and preimplantation genetic testing for aneuploidy (PGT-A) between January 2016 and December 2021 in a private IVF center. Out of the 517 embryos categorized as inconclusive, 400 survived intact to the warming procedure, re-expanded, and were suitable for rebiopsy. Of them, 71 rebiopsied blastocysts were transferred. Factors affecting the probability of obtaining an undiagnosed blastocyst and clinical outcomes from blastocysts biopsied once and twice were investigated.

Results

The overall diagnostic rate was 97.1%, with 517 blastocysts receiving inconclusive reports. Sever

SUBMITTER: Nohales M 

PROVIDER: S-EPMC10371936 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature