Left-ventricular volumes and ejection fraction from cardiac ECG-gated ¹⁵O-water positron emission tomography compared to cardiac magnetic resonance imaging using simultaneous hybrid PET/MR.

ABSTRACT:

Background

¹⁵O-water PET is the gold standard for noninvasive quantification of myocardial blood flow. In addition to evaluation of ischemia, the assessment of cardiac function and remodeling is important in all cardiac diseases. However, since ¹⁵O-water is freely diffusible and standard uptake images show little contrast between the myocardium and blood pool, the assessment of left-ventricular (LV) volumes and ejection fraction (EF) is challenging. Therefore, the aim of the present study was to investigate the feasibility of calculating LV volumes and EF from first-pass analysis of ¹⁵O-water PET, by comparison with cardiac magnetic resonance imaging (CMR) using a hybrid PET/MR scanner.

Methods

Twenty-four patients with known or suspected CAD

SUBMITTER: Nordstrom J 

PROVIDER: S-EPMC10372106 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature