Ontology highlight
ABSTRACT:
SUBMITTER: Gainullina A
PROVIDER: S-EPMC10372199 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Gainullina Anastasiia A Mogilenko Denis A DA Huang Li-Hao LH Todorov Helena H Narang Vipin V Kim Ki-Wook KW Yng Lim Sheau LS Kent Andrew A Jia Baosen B Seddu Kumba K Krchma Karen K Wu Jun J Crozat Karine K Tomasello Elena E Dress Regine R See Peter P Scott Charlotte C Gibbings Sophie S Bajpai Geetika G Desai Jigar V JV Maier Barbara B This Sébastien S Wang Peter P Aguilar Stephanie Vargas SV Poupel Lucie L Dussaud Sébastien S Zhou Tyng-An TA Angeli Veronique V Blander J Magarian JM Choi Kyunghee K Dalod Marc M Dzhagalov Ivan I Gautier Emmanuel L EL Jakubzick Claudia C Lavine Kory K Lionakis Michail S MS Paidassi Helena H Sieweke Michael H MH Ginhoux Florent F Guilliams Martin M Benoist Christophe C Merad Miriam M Randolph Gwendalyn J GJ Sergushichev Alexey A Artyomov Maxim N MN
Cell reports 20230127 2
The diversity of mononuclear phagocyte (MNP) subpopulations across tissues is one of the key physiological characteristics of the immune system. Here, we focus on understanding the metabolic variability of MNPs through metabolic network analysis applied to three large-scale transcriptional datasets: we introduce (1) an ImmGen MNP open-source dataset of 337 samples across 26 tissues; (2) a myeloid subset of ImmGen Phase I dataset (202 MNP samples); and (3) a myeloid mouse single-cell RNA sequenci ...[more]