Dissociation of energy connectivity and functional connectivity in Alzheimer's disease is associated with maintenance of cognitive performance.

ABSTRACT: The correlation between functional connectivity (FC) network segregation, glucose metabolism and cognitive decline has been recently identified. The coupling relationship between glucose metabolism and the intensity of neuronal activity obtained using hybrid PET/MRI techniques can provide additional information on the physiological state of the brain in patients with AD and mild cognitive impairment (MCI). It is a valuable task to use the above rules for constructing biomarkers that are closely related to the cognitive ability of individuals to monitor the pathological status of patients. This study proposed the concept of the energy connectivity (EC) network and its construction method. We hypothesized that the dissociation between energy connectivity and functional connectivity of brain

SUBMITTER: Sheng J 

PROVIDER: S-EPMC10372235 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature