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Bacterial Meningitis Caused by Bacillus subtilis var. natto.


ABSTRACT: A 67-year-old woman with a 2-day history of a fever, headache and disturbed consciousness was admitted to our hospital. Bacillus subtilis was isolated from both the cerebrospinal fluid and blood. She was cured by the administration of vancomycin. Next-generation sequencing identified the strain as B. subtilis var. natto, the same strain found in natto, which this patient ate daily. We suspected that some of the B. subtilis that caused the infection may have actually been B. subtilis var. natto.

SUBMITTER: Tokano M 

PROVIDER: S-EPMC10372276 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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Bacterial Meningitis Caused by Bacillus subtilis var. natto.

Tokano Mieko M   Tarumoto Norihito N   Imai Kazuo K   Sakai Jun J   Maeda Takuya T   Kawamura Toru T   Seo Kazuhide K   Takahashi Kazushi K   Yamamoto Toshimasa T   Maesaki Shigefumi S  

Internal medicine (Tokyo, Japan) 20221123 13


A 67-year-old woman with a 2-day history of a fever, headache and disturbed consciousness was admitted to our hospital. Bacillus subtilis was isolated from both the cerebrospinal fluid and blood. She was cured by the administration of vancomycin. Next-generation sequencing identified the strain as B. subtilis var. natto, the same strain found in natto, which this patient ate daily. We suspected that some of the B. subtilis that caused the infection may have actually been B. subtilis var. natto. ...[more]

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