Rotavirus-Associated Hospitalization in Children With Subsequent Autoimmune Disease.

ABSTRACT:

Importance

Rotavirus infection is a common cause of gastroenteritis in children that can trigger autoimmune processes, but the nature of this interaction remains poorly understood.

Objective

To estimate the association of rotavirus infection with the risk of subsequent autoimmune disease.

Design, setting, and participants

This population-matched cohort study used data from children and adolescents (aged younger than 18 years) in South Korea (national registers from January 1, 2002, to December 31, 2017). The cohort consisted of 86 157 patients in the exposure group who had experienced rotavirus-associated hospitalization and the same number of matched patients in the unexposed group. Data analyses were from May 1, 2020, through October 20, 2022.

Exposures

Hospi

SUBMITTER: Ha EK 

PROVIDER: S-EPMC10372702 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature