Ontology highlight
ABSTRACT:
SUBMITTER: Nishikino T
PROVIDER: S-EPMC10372836 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Nishikino Tatsuro T Hijikata Atsushi A Kojima Seiji S Shirai Tsuyoshi T Kainosho Masatsune M Homma Michio M Miyanoiri Yohei Y
iScience 20230711 8
The FliG protein plays a pivotal role in switching the rotational direction of the flagellar motor between clockwise and counterclockwise. Although we previously showed that mutations in the Gly-Gly linker of FliG induce a defect in switching rotational direction, the detailed molecular mechanism was not elucidated. Here, we studied the structural changes in the FliG fragment containing the middle and C-terminal regions, named FliG<sub>MC</sub>, and the switch-defective FliG<sub>MC</sub>-G215A, ...[more]