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Application of neurotransmitters and dental stem cells for pulp regeneration: A review.


ABSTRACT:

Introduction

Although there have been many studies on stem cells, few have investigated how neurotransmitters and stem cell proliferation interact to regenerate dental pulp. Dental pulp regeneration is an innovative procedure for reviving dental pulp, if feasible for the entire tooth. Upon tooth injury, activated platelets release serotonin and dopamine in bulk to mobilize dental pulp stem cells to mediate natural dental repair. This has induced research on the role of neurotransmitters in increasing the proliferation rate of stem cells. This review also covers prospective future treatments for dental pulp regeneration.

Methods

A literature search was performed via PubMed and ScienceDirect from 2001 to 2022, using the keywords "neurotransmitter," "stem cell," "tooth regenera

SUBMITTER: Ramli H 

PROVIDER: S-EPMC10373085 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature