Using pre-selected variants from large-scale whole-genome sequence data for single-step genomic predictions in pigs.

ABSTRACT:

Background

Whole-genome sequence (WGS) data harbor causative variants that may not be present in standard single nucleotide polymorphism (SNP) chip data. The objective of this study was to investigate the impact of using preselected variants from WGS for single-step genomic predictions in maternal and terminal pig lines with up to 1.8k sequenced and 104k sequence imputed animals per line.

Methods

Two maternal and four terminal lines were investigated for eight and seven traits, respectively. The number of sequenced animals ranged from 1365 to 1491 for the maternal lines and 381 to 1865 for the terminal lines. Imputation to sequence occurred within each line for 66k to 76k animals for the maternal lines and 29k to 104k animals for the terminal lines. Two preselected SNP sets

SUBMITTER: Jang S 

PROVIDER: S-EPMC10373252 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature