Non-coding RNAs identification and regulatory networks in pathogen-host interaction in the microsporidia congenital infection.

ABSTRACT:

Background

The interaction networks between coding and non-coding RNAs (ncRNAs) including long non-coding RNA (lncRNA), covalently closed circular RNA (circRNA) and miRNA are significant to elucidate molecular processes of biological activities and interactions between host and pathogen. Congenital infection caused by vertical transmission of microsporidia N. bombycis can result in severe economic losses in the silkworm-feeding industry. However, little is known about ncRNAs that take place in the microsporidia congenital infection. Here we conducted whole-transcriptome RNA-Seq analyses to identify ncRNAs and regulatory networks for both N. bombycis and host including silkworm embryos and larvae during the microsporidia congenital infection.

Results

A total of 4,171 mRNAs, 4

SUBMITTER: Shen Z 

PROVIDER: S-EPMC10373312 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature