Hematoma expansion in intracerebral hemorrhage - the right target?

ABSTRACT:

Background

The avoidance of hematoma expansion is the most important therapeutic goal during acute care of patients with intracerebral hemorrhage. Hematoma expansion occurs in up to 20-40% of patients and leads to poorer patient outcome in one of the most severe sub-types of stroke.

Main text

At current, randomized controlled trials have failed to provide evidence for interventions that effectively improve functional outcome in patients with intracerebral hemorrhage. Hence, hematoma expansion may serve as important surrogate target that appears causally linked with a poorer prognosis. Therefore, reduction of hematoma expansion rates will eventually translate to improved patient outcome overall. Recent years have shed light on the importance of early and aggressive treatment

SUBMITTER: Haupenthal D 

PROVIDER: S-EPMC10373350 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature