Immunomodulatory role of spleen tyrosine kinase in chronic inflammatory and autoimmune diseases.

ABSTRACT:

Background

The high prevalence of chronic inflammatory diseases or autoimmune reactions is a major source of concern and affects the quality of life of patients. Chronic inflammatory or autoimmune diseases are associated with many diseases in humans, including asthma, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease and cancer. Splenic tyrosine kinase (SYK) is a non-receptor tyrosine kinase that plays an important role in immune receptor signalling in immune and inflammatory responses.

Methods

This is a review article in which we searched for keywords "splenic tyrosine kinase", "inflammation" and "autoimmune diseases" in published literature such as Pubmed and Web of Science to collect relevant information and then conducted a study focusing on

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC10373573 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature