Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort.

ABSTRACT:

Objectives

High altitude exposure decreases the incidence of obesity and metabolic syndrome, but increases the expression of the thermogenic adipokines (leptin, fat cell fatty acid-binding protein (A-FABP) and visfatin). This study investigated the correlation of these adipokines with obesity and metabolic syndrome (MetS) in populations residing in a plateau-specific environment.

Design

Case-control study.

Setting

We cross-sectionally analysed data from the China Multi-Ethnic Cohort.

Participants

A total of 475 obese (OB, body mass index (BMI)≥28.0 kg/m²) plateau Han people and 475 age, sex and region-matched non-obese (NO, 18.5≤BMI<24.0 kg/m²) subjects were recruited. MetS was defined according to the National Cholesterol Education Progra

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC10373706 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature