Danish study of Non-Invasive Testing in Coronary Artery Disease 3 (Dan-NICAD 3): study design of a controlled study on optimal diagnostic strategy.

ABSTRACT:

Introduction

Current guideline recommend functional imaging for myocardial ischaemia if coronary CT angiography (CTA) has shown coronary artery disease (CAD) of uncertain functional significance. However, diagnostic accuracy of selective myocardial perfusion imaging after coronary CTA is currently unclear. The Danish study of Non-Invasive testing in Coronary Artery Disease 3 trial is designed to evaluate head to head the diagnostic accuracy of myocardial perfusion imaging with positron emission tomography (PET) using the tracers ⁸²Rubidium (⁸²Rb-PET) compared with oxygen-15 labelled water PET (¹⁵O-water-PET) in patients with symptoms of obstructive CAD and a coronary CT scan with suspected obstructive CAD.

Methods and analysis

This prospectiv

SUBMITTER: Winther S 

PROVIDER: S-EPMC10373750 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature