Comparison of mechanical properties and host tissue response to OviTex™ and Strattice™ surgical meshes.

ABSTRACT:

Purpose

This study compared the in vitro/benchtop and in vivo mechanical properties and host biologic response to ovine rumen-derived/polymer mesh hybrid OviTex™ with porcine-derived acellular dermal matrix Strattice™ Firm.

Methods

OviTex 2S Resorbable (OviTex 2S-R) and Strattice morphology were examined in vitro using histology and scanning electron microscopy; mechanical properties were assessed via tensile test; in vivo host biologic response and explant mechanics were evaluated in a rodent subcutaneous model. Separately, OviTex 1S Permanent (OviTex 1S-P) and Strattice were evaluated in a primate abdominal wall repair model.

Results

OviTex 2S-R demonstrated layer separation, whereas Strattice retained its structural integrity and demonstrated higher maximum load th

SUBMITTER: Lombardi J 

PROVIDER: S-EPMC10374700 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature