Differential diagnosis of lymphoma with ¹⁸F-FDG PET/CT in patients with fever of unknown origin accompanied by lymphadenopathy.

ABSTRACT:

Purpose

To investigate the value of ¹⁸F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) in the differential diagnosis of lymphoma in patients with fever of unknown origin (FUO) accompanied by lymphadenopathy and to develop a simple scoring system to distinguish lymphoma from other etiologies.

Methods

A prospective study was conducted on patients with classic FUO accompanied by lymphadenopathy. After standard diagnostic procedures, including PET/CT scan and lymph-node biopsy, 163 patients were enrolled and divided into lymphoma and benign groups according to the etiology. The diagnostic utility of PET/CT imaging was evaluated, and beneficial parameters that could improve diagnostic effectiveness were identified.

SUBMITTER: Chen J 

PROVIDER: S-EPMC10374793 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature