Rapid prototyping of high-resolution large format microfluidic device through maskless image guided in-situ photopolymerization.

ABSTRACT: Microfluidic devices have found extensive applications in mechanical, biomedical, chemical, and materials research. However, the high initial cost, low resolution, inferior feature fidelity, poor repeatability, rough surface finish, and long turn-around time of traditional prototyping methods limit their wider adoption. In this study, a strategic approach to a deterministic fabrication process based on in-situ image analysis and intermittent flow control called image-guided in-situ maskless lithography (IGIs-ML), has been proposed to overcome these challenges. By using dynamic image analysis and integrated flow control, IGIs-ML provides superior repeatability and fidelity of densely packed features across a large area and multiple devices. This general and robust approach enables the fabri

SUBMITTER: Paul R 

PROVIDER: S-EPMC10374892 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature