Frailty alone and interactively with obesity predicts heart failure: Kuopio Ischaemic Heart Disease Risk Factor Study.

ABSTRACT:

Aims

We aim to evaluate the association of frailty and high body mass index with risk of incident heart failure.

Methods and results

From the Kuopio Ischaemic Heart Disease Risk Factor Study, 408 women and 369 men, aged 61-74 years were included in this study. Frailty was ascertained with the presence of 3-5 and prefrailty 1-2 of the following criteria: weight loss (highest 20% over 7 years), self-reported tiredness, weakness (measured by handgrip strength), slow walking speed (walking pace), and low physical activity (lowest 20%). At the baseline, participants were allocated to frail (n = 36), prefrail (n = 340), and robust (n = 441). HF incidents were obtained by record linkages from the national hospitalization registry in Finland up to 31 December 2019. Multivariate Cox

SUBMITTER: Tajik B 

PROVIDER: S-EPMC10375090 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature