Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China.

ABSTRACT:

Background/objectives

This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine.

Subjects/methods

A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates.

Results

During a three-year follow-up, the age-adjusted i

SUBMITTER: Ning F 

PROVIDER: S-EPMC10375332 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature