Postprandial Metabolic Mesponses to High-fat Feeding in Healthy Adults Following Ingestion of Oolong Tea-Derived Polymerized Polyphenols: A Randomized, Double-blinded, Placebo-controlled Crossover Study.

ABSTRACT:

Background

Polymerized polyphenols (PP) found in oolong tea can inhibit pancreatic lipase activity in vitro, and pilot work indicates that this may reduce postprandial lipemia. Since tea contains caffeine and catechins, the interactions between these ingredients and PP warrant investigation.

Objectives

To assess whether PP ingested alone or with caffeine and catechins lowers postprandial lipemia.

Methods

Fifty healthy adults [mean (SD) age: 26 (7) y; BMI (in kg/m²): 24.0 (2.7); female: n = 16] completed 4 oral lipid tolerance tests in a placebo-controlled randomized, crossover design. Participants ingested 40 g of fat with either 1) placebo, 2) 100 mg PP, 3) 150 mg PP, or 4) 100 mg PP plus 50 mg caffeine and 63 mg catechins (PP + CC). Blood was sampled for

SUBMITTER: Perkin OJ 

PROVIDER: S-EPMC10375459 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature