Contrast-enhanced mammography in the assessment of residual disease after neoadjuvant treatment.

ABSTRACT:

Purpose

To investigate the utility of contrast-enhanced mammography (CEM) as an alternative to breast MRI for the evaluation of residual disease after neoadjuvant treatment (NAT).

Methods

This prospective study enrolled consecutive women undergoing NAT for breast cancer from July 2017-July 2019. Breast MRI and CEM exams performed after completion of NAT were read independently by two breast radiologists. Residual disease and lesion size on MRI and CEM recombined (RI) and low-energy images (LEI) were compared. Histopathology was considered the reference standard. Statistical analysis was performed using McNemar's and Leisenring's tests. Multiple comparison adjustment was made using Bonferroni procedure. Lesion sizes were correlated using Kendall's tau coefficient.

Results<

SUBMITTER: Hogan MP 

PROVIDER: S-EPMC10375516 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature