Genome-Wide Identification, Evolutionary and Mutational Analysis of the Buffalo Sox Gene Family.

ABSTRACT: The Sox gene family constitutes transcription factors with a conserved high mobility group box (HMG) that regulate a variety of developmental processes, including sex differentiation, neural, cartilage, and early embryonic development. In this study, we systematically analyzed and characterized the 20 Sox genes from the whole buffalo genome, using comparative genomic and evolutionary analyses. All the buffalo Sox genes were divided into nine sub-groups, and each gene had a specific number of exons and introns, which contributed to different gene structures. Molecular phylogeny revealed more sequence similarity of buffalo Sox genes with those of cattle. Furthermore, evolutionary analysis revealed that the HMG domain remained conserved in the all members of the Sox gene family. Similarly, al

SUBMITTER: Abdullah M 

PROVIDER: S-EPMC10376873 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature